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Viagra vs Cialis vs Levitra
Viagra, Cialis and Levitra are PDE5-inhibiting orally administered drugs meant to treat male sexual function disability. All three medications received FDA approval and are effective for achieving and maintaining an erection.
As phosphodiesterase type 5 inhibitors, Viagra, Cialis and Levitra block the degradative influence of PDE type 5 in the cells of smooth muscle which line the blood vessels of the penis. After sexual stimulation the nitrate oxide is released, resulting in the relaxation of the muscle and a more intense blood flow into the penis, i.e., erection. That is why, drugs containing PDE5-inhibiting substances that widen the vessels are successfully used for treating erectile dysfunction.
Viagra, Cialis and Levitra act only after sexual stimulation. In means that taking these medications you will have an erection only when you are with your partner, in the appropriate time and place, and not when you are driving or sitting in a restaurant.
Viagra – or sildenafil – was patented in 1993 by Pfizer and, after numerous clinic studies being conducted, the drug received FDA approval in 1998. Originally Viagra was developed to treat heart disease and angina, but during medical trials volunteers reported some unexpected side-effects. By nowadays Viagra has been tested by more than 23 million of men of different ages. The medication comes in 25mg, 50mg and 100mg pills and should be used on empty stomach, from 30 minutes to 4 hours before anticipated sexual activity. The action lasts up to 5 hours. Among the most common side effects upset stomach, face flushing, headache and dizziness should be mentioned.
Cialis, known under the generic name of tadalafil, was patented in 2002 by Lilly ICOS. It has been tested by about 15,000 men who participated in clinic trials, let alone more than 8 million of men worldwide who chose this drug for ED treatment and found it efficient. Cialis comes in 2.5mg, 5mg, 10mg, and 20mg pills and is usually taken 30 minutes before having sex. Cialis has the same side effects and list of interactions as Viagra and Levitra, but is distinguished by the exceptional durability of its action: up to 36 hours. Moreover, in 2007 Lilly ICOS carried out a clinical development program and ascertained that chronic use of Cialis (2.5mg-5mg) was available for those who suffered from ED but didn't want to lose the spontaneity of sexual relationships.
Levitra (vardenafil) was patented in 2001 by Bayer. To believe clinic studies, Levitra works more efficiently than Viagra, because it needs only 16 minutes to cause an erection, while the effect lasts up to 6 hours. In addition, Levitra doesn't have either food or drink limitation. As for the price, Levitra is more expensive than Viagra and Cialis. The drug has the same side effects as Cialis and Viagra, which are provoked by the PDE5-inhibiting substance being present.
No head-to-head comparison tests of Viagra, Cialis and Levitra have been conducted yet. Nevertheless, a few main differences can be mentioned. The most long-lasting ED medication is Cialis, with its 36 hours, then 6-hour Levitra follows, and Viagra (up to 5 hours) is the least durable one of three. Viagra, Cialis and Levitra showed on average 70% result, so considering efficiency in ED treatment, all these drugs are helpful. Viagra and Cialis aren't recommended to be mixed with food, while with Levitra romantic dinners are still possible. Viagra, Cialis and Levitra have the same side effects, such as headache, facial rash and upset stomach, but Viagra may also provoke blue discoloration of vision, while Cialis sometimes leads to muscle aches (not more than 5% of patients). The most popular of the three is Viagra which had a very powerful promotional campaign, however, Cialis and Levitra, featuring better characteristics, are widely known as well.